Important Safety Information

Please see Important Safety Information below for intended use, potential risks and side effects, use in specific populations, and drug interactions of advertised prescription treatments.

Maves encourages the reporting of any adverse side effects of medications to the medical professional and the distributing pharmacy. Additionally, to report suspected adverse reactions to acarbose contact the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

In case of emergencies, please call 911 or go seek care at the nearest emergency room.

Compounded GLP‑1 (semaglutide)

*Compounded medications may be prescribed by physicians but have not been FDA regulated for safety, effectiveness, or quality. FDA-approved medicines containing semaglutide are available.‍

WARNING

Please contact your doctor ASAP and seek in-person care immediately if a side effect becomes problematic or you experience:

• Severe nausea and/or vomiting resulting in dehydration—it is important to stay well hydrated and drink plenty of fluids while on this medication
  Kidney problems/kidney failure - vomiting, nausea, diarrhea can cause dehydration and kidney issues and make kidney problems worse in individuals who have pre-existing kidney conditions; may sometimes lead to the need for hemodialysis
• Thyroid C-Cell Tumor: Trouble swallowing, hoarseness, a lump or swelling in your neck, or shortness of breath (see black box warning below)
• Pancreatitis: Severe pain in your abdomen or back that will not go away
• Acute gallbladder disease - Pain in the middle or right upper stomach, fever, white parts of your eyes turn yellow or skin turns yellow, nausea/vomiting. If gallstones or inflammation of the gallbladder is suspected further studies are needed.
• Hepatitis/Elevated liver enzymes/Jaundice
• Diabetic retinopathy problems: Changes in vision in those with type II diabetes, particularly vision problems may worsen in those with a history of diabetic retinopathy
• Severe gastrointestinal disease - may cause gastrointestinal disease; do not use if you have a history of severe gastrointestinal disease
• Signs of low blood sugar (for example, dizziness, weakness, shakiness, jitteriness, headache, anxiety/mood changes, rapid heartbeat, confusion, slurred speech, sweating, or lightheadedness). While this is rare with GLP-1s, if it occurs, please seek in-person care immediately. If you have these symptoms, try having liquid or food containing sugar (around 15-20 grams) —drinking juice, having regular soda, or eating some hard candies right away, as this will help raise your blood sugar quickly. If taken with insulin or an insulin secretagogue (i.e. sulfonylurea such as Glipizide, glimepiride, and glyburide) it is best to talk to your healthcare provider about possibly lowering the dose of these medications to lower the risk of hypoglycemia.
• Increasing heart rate
• Worsening depression, behavior changes, or suicidality

Never share the semaglutide with other people.

Drug Interactions

As with other medications, compounded semaglutide can interact with alcohol and certain prescription and non-prescription medications and herbal products. The risk of hypoglycemia is increased when combined with insulin or insulin secretagogues such as sulfonylureas. Compounded semaglutide delays gastric emptying and may impact the absorption of oral medications. If you are on papillary hormone medication, prior to starting compounded semaglutide, please review the timing of taking your papillary hormone medication with the doctor who prescribes it as it may need to be adjusted. The drug levels of medications with narrow therapeutic windows (ie warfarin) should be monitored closely while on compounded semaglutide.

Please consult the pharmaceutical packaging for a full list of side effects, warnings, interactions and additional information.

To report suspected adverse reactions to compounded semaglutide, contact the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

In case of emergencies, please call 911 or go to the nearest emergency room.

Note: The above statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

BLACK BOX WARNING

GLP-1s are contraindicated in individuals with a history of medullary thyroid carcinoma, a family history of such, or in patients with multiple endocrine neoplasia syndrome type 2. Do not take them if you have ever had thyroid cancer. In studies with rodents, GLP-1s caused thyroid tumors, including thyroid cancer; it is not known if they will cause thyroid tumors or cancer in humans. Please notify your doctor ASAP if you develop trouble swallowing, hoarseness, a lump or swelling in your neck, or shortness of breath.

If you experience a medical emergency, call 911 or go to the nearest emergency room.

Tell your healthcare provider about your medical history prior to taking semaglutide.

Avoid alcohol while taking this medication. If you’re taking diabetes medications, please discuss this with your prescribing doctor before starting semaglutide, as your diabetes medications may need to be adjusted as you lose weight.

Use adequate contraception while taking this medication. Do not take this medication if pregnant, trying to get pregnant or breastfeeding. If you plan to become pregnant, this medication needs to be stopped at least 2 months before trying. This medication may cause fetal harm.

Notify your doctor if you have kidney, liver, or pancreas problems.

Stop using semaglutide and call your healthcare provider immediately if you have severe stomach or abdomen pain that will not go away, with or without vomiting.

Stop using semaglutide and get medical help right away if you have any symptoms of a serious allergic reaction, including swelling of your face, lips, tongue, or throat; problems breathing or swallowing; severe rash or itching; fainting or feeling dizzy; or very rapid heartbeat.

Serious hypersensitivity reactions (e.g., anaphylaxis and angioedema) have been reported. Discontinue semaglutide if suspected and promptly seek medical advice.

Compounded GLP‑1+GIP (tirzepatide)

*Compounded medications may be prescribed by physicians but have not been FDA regulated for safety, effectiveness, or quality. FDA-approved medicines containing trizepatide are available.‍

WARNING

Compounded tirzepatide usage has been associated with the potential development of thyroid tumors, including thyroid cancer. Watch for any potential symptoms, such as neck lumps or swelling, hoarseness, difficulty swallowing, or breathlessness. Should any of these symptoms arise, it is imperative to inform your healthcare provider promptly.

Avoid using compounded tirzepatide if you or any family members have a history of medullary thyroid carcinoma (MTC), a specific type of thyroid cancer. Similarly, refrain from its use if diagnosed with Multiple Endocrine Neoplasia syndrome type 2 (MEN 2), or if you've previously experienced a severe allergic reaction to tirzepatide or any of its components.

Serious Side Effects

Compounded tirzepatide carries the risk of severe side effects, which include:

• Gastrointestinal Issues: Reports indicate the possibility of severe stomach problems associated with compounded tirzepatide usage. Notify your healthcare provider if you experience persistent or severe stomach discomfort.
• Kidney Complications: Diarrhea, nausea, and vomiting may lead to dehydration, potentially resulting in kidney problems. Adequate fluid intake is crucial to mitigate this risk.
• Gallbladder Concerns: Some individuals may encounter gallbladder problems while using compounded tirzepatide. Seek immediate medical attention if symptoms such as upper abdominal pain, fever, jaundice, or changes in stool color occur.
• Pancreatitis: Discontinue use and contact your healthcare provider if you experience persistent abdominal pain, with or without vomiting, as it could indicate inflammation of the pancreas.
• Allergic Reactions: Cease compounded tirzepatide usage and seek urgent medical assistance if you develop symptoms of a severe allergic reaction, including facial swelling, breathing difficulties, rash, or rapid heartbeat.
• Hypoglycemia: The risk of low blood sugar may increase when using compounded tirzepatide alongside medications that lower blood sugar levels. Recognizable symptoms include dizziness, sweating, confusion, and rapid heartbeat.
• Vision Changes: Notify your healthcare provider of any alterations in vision observed during tirzepatide treatment.
• Depression or Suicidal Thoughts: Pay close attention to changes in mood or mental state while using tirzepatide, and promptly report any concerns to your healthcare provider.

Common Side Effects

The most frequently reported side effects of compounded tirzepatide include:

• Nausea
• Diarrhea
• Vomiting
• Constipation
• Abdominal pain
• Indigestion
• Injection site reactions
• Fatigue
• Allergic reactions
• Belching
• Hair loss
• Heartburn

These side effects are not exhaustive. Should you experience any persistent or bothersome side effects, discuss them with your healthcare provider for appropriate management.

Tell your healthcare provider if you have any side effects. 

To report suspected severe side effects or adverse reactions to compounded trizepatide, contact the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch. In case of emergencies, please call 911 or go to the nearest emergency room.

Drug Interactions

As with other medications, compounded trizepatide can interact with alcohol and certain prescription and non-prescription medications and herbal products. The risk of hypoglycemia is increased when combined with insulin or insulin secretagogues such as sulfonylureas. Compounded trizepatide delays gastric emptying and may impact the absorption of oral medications. If you are on papillary hormone medication, prior to starting compounded trizepatide, please review the timing of taking your papillary hormone medication with the doctor who prescribes it as it may need to be adjusted. The drug levels of medications with narrow therapeutic windows (ie warfarin) should be monitored closely while on compounded trizepatide.

Please consult the pharmaceutical packaging for a full list of side effects, warnings, interactions and additional information.

Tirzepatide may alter the efficacy of birth control pills. Talk with your doctor before starting tirzepatide if you are on birth control. Your healthcare provider may recommend another type of birth control for 4 weeks after you start tirzepatide and for 4 weeks after each increase in your dose.

Note: The above statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.‍

NAD+

Common Side Effects‍

NAD+ Injection

• Redness, tenderness, or soreness at the injection site
• Mild flushing or warmth
• Lightheadedness
• Temporary fatigue
• Mild nausea

NAD+ Nasal Spray

• Nasal dryness or irritation
• Sneezing or transient burning sensation
• Headache
• Mild dizziness

NAD+ Face Cream

• Skin sensitivity at the application site
• Temporary redness or tingling
• Dryness or irritation, especially with overuse

NAD+ Patch

• Skin irritation under or around the patch
• Itching or redness at the application site

These effects are generally mild and short-lived. Rotate application or injection sites and follow provider guidance to reduce the risk of irritation.

More Serious Side Effects (less common)

• Allergic reaction (rash, swelling, shortness of breath)
• Dizziness or fainting (especially post-injection)
• Persistent fatigue or flu-like symptoms
• Flushing with rapid heartbeat

If you experience signs of an allergic reaction or severe discomfort, stop treatment and seek medical care immediately.

Warnings (serious risks)

• Do not exceed the dose prescribed by your provider
• NAD+ injection should be administered subcutaneously; improper technique may lead to increased irritation or localized reaction
• Use nasal spray formulations carefully to avoid irritation or overuse
• Individuals with autoimmune, cardiovascular, or metabolic conditions should be monitored more closely

Contraindications (not recommended for)

• Individuals with known hypersensitivity to NAD+ or formulation components
• People currently pregnant or breastfeeding
• Anyone with active infection, uncontrolled chronic illness, or ongoing cancer treatment without prior approval from their specialist

Drug Interactions

• No widely reported drug interactions, but NAD+ may affect oxidative metabolism and mitochondrial function
• Use caution if you are taking medications that impact energy metabolism, including insulin, metformin, or corticosteroids
• Always disclose all prescription medications, supplements, and herbal products to your provider during your consultation

Pregnancy & Breastfeeding

NAD+ products are not recommended during pregnancy or while breastfeeding, as safety data in these populations is limited. Discuss alternative options with your provider if you are planning to become pregnant or nursing.

Storage

• Injection: Store in the refrigerator (2–8°C / 36–46°F). Do not freeze. Protect from light.

Keep all formulations out of reach of children. Do not use any product past its expiration date.

Have Questions?

Patients should consult their healthcare provider if they have any questions about their dosing, formulation type, side effects, or treatment options. Never modify or exceed the dosing schedule without medical supervision.

Disclaimer: The NAD+ formulations offered through Eden are compounded and prescribed off-label by licensed providers. These medications are not approved by the FDA. Statements above are for educational purposes and have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.

Sermorelin

Safety Information:

Side effects are typically mild and go away over time.

Common Side Effects

• Fatigue or mild dizziness
• Sermorelin injection: Pain, redness, or swelling at the injection site
• Sermorelin ODT: Temporary changes in taste or dry mouth after taking the tablet

Less Side Effects 

Some rare side effects may include:

• Itching
• Trouble swallowing
• Dizziness
• Flushing
• Headache
• Sleepiness or fatigue
• Hyperactivity or restlessness

Most of these effects are temporary and resolve with continued use. Contact your provider if any symptom becomes bothersome or does not go away.

Warnings (serious risks)

Sermorelin may affect hormone levels and metabolism. Regular monitoring is important to detect changes early. Use caution if you have a history of metabolic or endocrine conditions. Though rare, allergic reactions are possible.

Contraindications

You should not use Sermorelin if:

• You have a known hypersensitivity to Sermorelin or any of its ingredients
• You are currently pregnant or are planning to become pregnant
• You are breastfeeding
• You have active cancer or a history of cancer not in remission

Drug Interactions

Sermorelin may interact with:

• Glucocorticoids (e.g., prednisone), which may blunt the effectiveness of growth hormone stimulation
• Thyroid medications, which may alter hormonal balance or interfere with monitoring

Always inform your provider about all medications and supplements you are currently taking.

Pregnancy & Breastfeeding

Sermorelin is not recommended during pregnancy or while breastfeeding. Its safety in these populations has not been established. Use effective contraception while on treatment unless otherwise directed by your provider.

Storage

• Sermorelin Injection: Store refrigerated at 2–8°C (36–46°F). Do not freeze. Protect from light.

Keep out of reach of children. Do not use after the expiration date printed on the packaging.

Have Questions?

Consult your healthcare provider if you have any questions about dosing, side effects, or treatment options.

Disclaimer: The statements above have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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Enclomophine

Safety Information

Enclomiphene is a medication that may be prescribed to increase testosterone levels in men experiencing symptoms of low testosterone. While it is FDA-approved for other uses, its application for treating low testosterone in men is considered off-label, meaning it is not specifically approved by the FDA for this purpose, though your healthcare provider may prescribe it when deemed appropriate. The purpose of this consent form is to ensure that you understand the reasons for using enclomiphene, the potential benefits and risks, the monitoring plan, and your responsibilities during treatment. Please read this document carefully. You have been diagnosed with symptoms suggestive of hypogonadism, such as fatigue, decreased libido, erectile dysfunction, mood changes, and reduced muscle mass. You may have low testosterone levels or testosterone levels within the normal range but with consistent symptoms, which is suggestive of functional hypogonadism. Enclomiphene is being considered as a treatment option to potentially improve your symptoms by stimulating your body’s natural production of testosterone. As previously mentioned, the use of enclomiphene to increase testosterone levels in men is off-label. Although this medication is legally prescribed, it is being used in a way that differs from its original FDA-approved indications.

Potential Benefits

The potential benefits of enclomiphene include: Increased testosterone levels Improved energy and mood Enhanced libido and sexual function Increased muscle mass and strength Potential improvement in fertility since enclomiphene does not suppress natural testosterone production.

Potential Risks and Side Effects

Potential risks and side effects include: Common risks: Increased risk of blood clots Mood changes Gynecomastia Elevated red blood cell count Headaches, nausea, and visual disturbances Prostate enlargement Worsening of pre-existing sleep apnea Serious but less common risks: Exacerbation of undiagnosed prostate cancer Severe cardiovascular events, such as heart attack or stroke Liver toxicity.

Monitoring Plan

To ensure safety and effectiveness, regular monitoring is required. This includes: Initial baseline testing to measure testosterone levels, liver function, and estradiol levels Ongoing monitoring with blood tests to assess treatment efficacy and safety Regular follow-up visits to discuss progress, side effects, and adjustments to your treatment plan.

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